New Groundhttps://new-ground.comNew Ground Newsfeedenhttps://new-ground.com/pix/new-ground.jpgNew Groundhttps://new-ground.com Research article: Immune response in autism, revealed by in-vivo studies of xenotransplanted human brain organoidsinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/immune-response-in-autism-revealed-by-in-vivo-studies-of-xenotransplanted-human-brain-organoids/new-ground.2023.16118 https://new-ground.com/en/articles/immune-response-in-autism-revealed-by-in-vivo-studies-of-xenotransplanted-human-brain-organoids/new-ground.2023.16118

Stem-cell-derived microglial cells in forebrain organoids, derived from stem cell lines from patients with ASD and macrocephaly and transplanted into the brains of mice, allowed to study in-vivo immune responses.

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]]> Thu, 19 Oct 2023 17:21:19 +0100 Opinion: The Point of Contention with Standard Cosmologyinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/the-point-of-contention-with-standard-cosmology/new-ground.2023.49421 https://new-ground.com/en/articles/the-point-of-contention-with-standard-cosmology/new-ground.2023.49421

A rapidly growing body of high-precision cosmological data has moved beyond the standard model’s ability to explain it. A possible culprit: the set of simplistic built-in assumptions which are poorly motivated by fundamental theory.

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]]> Fri, 06 Oct 2023 18:24:19 +0100 Research article: Formal thought disorder is associated with brain network changes across diagnosesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/formal-thought-disorder-is-associated-with-brain-network-changes-across-diagnoses/new-ground.2023.76793 https://new-ground.com/en/articles/formal-thought-disorder-is-associated-with-brain-network-changes-across-diagnoses/new-ground.2023.76793

For the first time, researchers were able to show that alterations in the structural networks of affective and psychotic disorder patients’ brains correlate with the patients’ symptoms and not with their diagnosis.

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]]> Sun, 06 Aug 2023 12:59:47 +0100 Research article: Single-Cell Analysis Supports a Role for T cell Autoimmunity in Atherosclerosis and Helps Pave the Way for New Immunotherapiesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/single-cell-analysis-supports-a-role-for-t-cell-autoimmunity-in-atherosclerosis-and-helps-pave-the-way-for-new-immunotherapies/new-ground.2023.99892 https://new-ground.com/en/articles/single-cell-analysis-supports-a-role-for-t-cell-autoimmunity-in-atherosclerosis-and-helps-pave-the-way-for-new-immunotherapies/new-ground.2023.99892

Research suggests a role for autoimmunity in atherosclerosis, a chronic inflammatory disease of the arteries. Now, single-cell analysis has shed new light on this connection and opened up potential avenues for new therapeutic interventions.

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]]> Fri, 09 Jun 2023 10:09:15 +0100 News: May 4, 2023: New Ground Fact Sheetinfo@new-ground.com (New Ground) https://new-ground.com/en/news/2023-05-04/may-4-2023-new-ground-fact-sheet/16 https://new-ground.com/en/news/2023-05-04/may-4-2023-new-ground-fact-sheet/16

Six months after launch, new-ground.com gains traction. A quick overview

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]]> Thu, 04 May 2023 09:46:17 +0100 Comment: Eight Significant Shortcomings of the Standard Model of Cosmologyinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/eight-significant-shortcomings-of-the-standard-model-of-cosmology/new-ground.2023.77033 https://new-ground.com/en/articles/eight-significant-shortcomings-of-the-standard-model-of-cosmology/new-ground.2023.77033

A new study points to ΛCDM's fundamental inconsistencies and to its conflicts with observations as well as with foundational principles of quantum mechanics, general relativity and particle physics. Its author calls for a complete revision of ΛCDM cosmology.

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]]> Sat, 07 Oct 2023 19:00:35 +0100 Research article: Superconductivity Experiments Confirm an Important Mechanism for Increasing the Maximum Critical Temperature in Cupratesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/superconductivity-experiments-confirm-an-important-mechanism-for-increasing-the-maximum-critical-temperature-in-cuprates/new-ground.2023.97097 https://new-ground.com/en/articles/superconductivity-experiments-confirm-an-important-mechanism-for-increasing-the-maximum-critical-temperature-in-cuprates/new-ground.2023.97097

Some cuprate superconductors exhibit high critical temperatures at atmospheric pressure. High-pressure nuclear magnetic resonance experiments on the cuprate YBCO have now provided crucial insights into the underlying process.

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]]> Mon, 20 Mar 2023 08:05:13 +0100 News: March 15, 2023: The uncovered gap between scholarly publishing and science news for the publicinfo@new-ground.com (New Ground) https://new-ground.com/en/news/2023-03-15/march-15-2023-the-uncovered-gap-between-scholarly-publishing-and-science-news-for-the-public/15 https://new-ground.com/en/news/2023-03-15/march-15-2023-the-uncovered-gap-between-scholarly-publishing-and-science-news-for-the-public/15

In a guest post on the Society for Scholarly Publishing's blog, New Ground's publisher reports on the journal's approach to presenting science and community feedback.

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]]> Thu, 04 May 2023 09:46:08 +0100 Research article: Deployment of Green Hydrogen: Opening a Probabilistic Feasibility Space to Inform Policy Choicesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/deployment-of-green-hydrogen-opening-a-probabilistic-feasibility-space-to-inform-policy-choices/new-ground.2023.80233 https://new-ground.com/en/articles/deployment-of-green-hydrogen-opening-a-probabilistic-feasibility-space-to-inform-policy-choices/new-ground.2023.80233

Green hydrogen can replace fossil fuels where direct electrification is unfeasible. Based on probabilistic methods and using growth rates of technology analogs, a recent study models a feasibility space for green hydrogen, assessing the likelihood that it will play a major role before 2050.

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]]> Mon, 13 Feb 2023 06:07:12 +0100 Research article: Multiple Sclerosis Associated with a Broad Repertoire of T Cell Receptors That Are Specific to Epstein-Barr Virusinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/multiple-sclerosis-associated-with-a-broad-repertoire-of-t-cell-receptors-that-are-specific-to-epstein-barr-virus/new-ground.2023.66524 https://new-ground.com/en/articles/multiple-sclerosis-associated-with-a-broad-repertoire-of-t-cell-receptors-that-are-specific-to-epstein-barr-virus/new-ground.2023.66524

Is infection with the Epstein-Barr virus the long-debated cause of multiple sclerosis? A new study found more TCRβ sequences specific to the virus in patients than in healthy individuals. These findings are consistent with the hypothesis that MS is associated with an ongoing immune response to the Epstein-Barr virus.

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]]> Thu, 26 Jan 2023 15:30:41 +0100 Research article: How to Efficiently Achieve Photonic Multi-Qubit Entanglementinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/how-to-efficiently-achieve-photonic-multi-qubit-entanglement/new-ground.2022.83669 https://new-ground.com/en/articles/how-to-efficiently-achieve-photonic-multi-qubit-entanglement/new-ground.2022.83669

Researchers have now developed a procedure to efficiently and reliably generate linear graph states with up to 14 entangled photons, all emitted from a single atom. Their findings bring one-way quantum computing hardware closer to our reach.

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]]> Sun, 02 Apr 2023 09:17:20 +0100 Research article: Catching the Epigenome in Action: A Global View on Gene Regulatory Logic in the Mouse Cortexinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/catching-the-epigenome-in-action-a-global-view-on-gene-regulatory-logic-in-the-mouse-cortex/new-ground.2022.63730 https://new-ground.com/en/articles/catching-the-epigenome-in-action-a-global-view-on-gene-regulatory-logic-in-the-mouse-cortex/new-ground.2022.63730

Gene regulatory networks in cells ensure the precise temporal and spatial regulation of gene expression. A recent multimodal epigenomics analysis shows that these networks are dynamically remodeled in the course of embryonic development.

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]]> Sun, 02 Apr 2023 09:07:51 +0100 Research article: Real-Time, Multicolor Fluorescence Imaging of Tumors in Tissuesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/real-time-multicolor-fluorescence-imaging-of-tumors-in-tissues/new-ground.2022.22694 https://new-ground.com/en/articles/real-time-multicolor-fluorescence-imaging-of-tumors-in-tissues/new-ground.2022.22694

Novel synthetic fluorescent dyes in combination with SWIR light allow the high-resolution imaging of tissues within living organisms. They surpass existing techniques in terms of penetration depth and also enable the simultaneous visualization of multiple tissue types.

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]]> Sun, 02 Apr 2023 07:46:05 +0100 Research article: Don’t Pack and Leave Too Soon: Forgiving Strategies of Cooperators Towards Defectors Can Lead to Cooperative Safe Havensinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/don-t-pack-and-leave-too-soon-forgiving-strategies-of-cooperators-towards-defectors-can-lead-to-cooperative-safe-havens/new-ground.2022.61212 https://new-ground.com/en/articles/don-t-pack-and-leave-too-soon-forgiving-strategies-of-cooperators-towards-defectors-can-lead-to-cooperative-safe-havens/new-ground.2022.61212

For spatially arranged ecological communities, mathematical analysis of the so-called snowdrift game shows that beneficial outcomes of migration strategies depend on the connectivity between habitats.

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]]> Tue, 22 Nov 2022 09:19:16 +0100 Research article: Multiple Sclerosis: What We Can Learn Even from Failed Approaches to Antibody Therapiesinfo@new-ground.com (New Ground) https://new-ground.com/en/articles/multiple-sclerosis-what-we-can-learn-even-from-failed-approaches-to-antibody-therapies/new-ground.2022.13902 https://new-ground.com/en/articles/multiple-sclerosis-what-we-can-learn-even-from-failed-approaches-to-antibody-therapies/new-ground.2022.13902

In recent years, the revolutionary effects of monoclonal antibodies on the immune response of multiple sclerosis patients have been studied extensively. But it's time to also learn from so-called “negative” studies.

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